BDBM50032351 3-(2'-Butyloxycarbonylsulfamoyl-3-chloro-biphenyl-4-ylmethyl)-5-ethyl-2-propyl-3H-imidazole-4-carboxylic acid methyl ester::CHEMBL304022::butyloxy 2-{2-[3-chloro-4-(4-ethyl-5-methyloxycarbonyl-2-propyl-1H-1-imidazolylmethyl)phenyl]phenylsulfonyl}carbonylamino

SMILES CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCC)nc(CC)c2C(=O)OC)c(Cl)c1

InChI Key InChIKey=AWIVWBRKOUQKEI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50032351   

TargetType-2 angiotensin II receptor(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50032351(3-(2'-Butyloxycarbonylsulfamoyl-3-chloro-biphenyl-...)
Affinity DataIC50: 37nMAssay Description:Inhibitory concentration against Angiotensin II receptor type 2 with [125I]-[Sar1,Ile8]Ang IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetType-2 angiotensin II receptor(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50032351(3-(2'-Butyloxycarbonylsulfamoyl-3-chloro-biphenyl-...)
Affinity DataIC50: 7nMAssay Description:Inhibition of [125I]-[Sar1,Ile8]Ang II binding at rat angiotensin II (type 2) receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetType-2 angiotensin II receptor(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50032351(3-(2'-Butyloxycarbonylsulfamoyl-3-chloro-biphenyl-...)
Affinity DataIC50: 7nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT2 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM50032351(3-(2'-Butyloxycarbonylsulfamoyl-3-chloro-biphenyl-...)
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]- Ang II from angiotensin II AT1 receptor in rat adrenal cortical microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article