BDBM50032334 CHEMBL3353541

SMILES C[C@@]1(CCN1C(=O)c2csc3c2cccc3)C(=O)N(CCCC(=O)O)Cc4cccc(c4)Cl

InChI Key InChIKey=MPMKMQHJHDHPBE-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50032334   

TargetFree fatty acid receptor 2(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50032334(CHEMBL3353541)
Affinity DataIC50: 483nMAssay Description:Antagonist activity against FFA2 receptor in human whole blood assessed as inhibition of sodium acetate-induced CD11b[AE] expression by flow cytometr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetFree fatty acid receptor 2(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50032334(CHEMBL3353541)
Affinity DataIC50: 9nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetFree fatty acid receptor 2(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50032334(CHEMBL3353541)
Affinity DataEC50:  12nMAssay Description:Agonist activity to human FFA2R expressed in HEK293T cells assessed as induction beta-arrestin-2 recruitment after 10 mins by BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed