BDBM50032162 3-[2-(1-Benzyl-piperidin-4-yl)-ethyl]-5,7-dihydro-isoxazolo[4,5-f]indol-6-one; compound with (Z)-but-2-enedioic acid::CHEMBL329012::CHEMBL359570

SMILES O=C1Cc2cc3c(CCC4CCN(Cc5ccccc5)CC4)noc3cc2N1

InChI Key InChIKey=MTCMTKNMZCPKLX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50032162   

TargetAcetylcholinesterase(Human)
Universidade Federal Do Rio De Janeiro (Ufrj)

Curated by ChEMBL
LigandPNGBDBM50032162(CHEMBL329012 | CHEMBL359570 | 3-[2-(1-Benzyl-piper...)
Affinity DataIC50: 0.331nMAssay Description:Inhibition of human acetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCholinesterase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50032162(CHEMBL329012 | CHEMBL359570 | 3-[2-(1-Benzyl-piper...)
Affinity DataIC50: 7.20E+3nMAssay Description:In vitro inhibition of Butyrylcholinesterase from human erythrocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidade Federal Do Rio De Janeiro (Ufrj)

Curated by ChEMBL
LigandPNGBDBM50032162(CHEMBL329012 | CHEMBL359570 | 3-[2-(1-Benzyl-piper...)
Affinity DataIC50: 0.330nMAssay Description:In vitro inhibition of Acetylcholinesterase from human erythrocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidade Federal Do Rio De Janeiro (Ufrj)

Curated by ChEMBL
LigandPNGBDBM50032162(CHEMBL329012 | CHEMBL359570 | 3-[2-(1-Benzyl-piper...)
Affinity DataIC50: 0.330nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidade Federal Do Rio De Janeiro (Ufrj)

Curated by ChEMBL
LigandPNGBDBM50032162(CHEMBL329012 | CHEMBL359570 | 3-[2-(1-Benzyl-piper...)
Affinity DataIC50: 0.330nMAssay Description:Inhibitory activity against Acetylcholinesterase enzyme using human AChE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed