BDBM50031935 8-Methoxy-6-(4-methyl-piperazin-1-yl)-benzo[k]phenanthridine::CHEMBL291771

SMILES COc1cc2c(nc3ccccc3c2c2ccccc12)N1CCN(C)CC1

InChI Key InChIKey=LDPNVJBXUQDGFQ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50031935   

Target5-hydroxytryptamine receptor 3A/3B(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50031935(8-Methoxy-6-(4-methyl-piperazin-1-yl)-benzo[k]phen...)
Affinity DataKi:  42nMAssay Description:Binding affinity for 5-hydroxytryptamine 3 receptor from rat cortex using [3H]BRL-43694 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50031935(8-Methoxy-6-(4-methyl-piperazin-1-yl)-benzo[k]phen...)
Affinity DataKi:  42nMAssay Description:Rat 5-hydroxytryptamine 3 receptor (5-HT3) antagonistMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50031935(8-Methoxy-6-(4-methyl-piperazin-1-yl)-benzo[k]phen...)
Affinity DataKi:  240nMAssay Description:Binding affinity to 5-hydroxytryptamine 2A receptor from rat cortex assayed using [3H]ketanserin as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50031935(8-Methoxy-6-(4-methyl-piperazin-1-yl)-benzo[k]phen...)
Affinity DataKi:  2.30E+3nMAssay Description:The compound was tested for their binding affinity towards 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed