BDBM50031934 6-(4-Methyl-piperazin-1-yl)-benzo[k]phenanthridine::CHEMBL41462

SMILES CN1CCN(CC1)c1nc2ccccc2c2c1ccc1ccccc21

InChI Key InChIKey=ASUOWQNSLNMXFU-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50031934   

Target5-hydroxytryptamine receptor 3A/3B(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50031934(6-(4-Methyl-piperazin-1-yl)-benzo[k]phenanthridine...)
Affinity DataKi:  9.5nMAssay Description:Binding affinity for 5-hydroxytryptamine 3 receptor from rat cortex using [3H]BRL-43694 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50031934(6-(4-Methyl-piperazin-1-yl)-benzo[k]phenanthridine...)
Affinity DataKi:  9.5nMAssay Description:Rat 5-hydroxytryptamine 3 receptor (5-HT3) antagonistMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50031934(6-(4-Methyl-piperazin-1-yl)-benzo[k]phenanthridine...)
Affinity DataKi:  46nMAssay Description:Inhibition of [3H]granisetron binding to 5-hydroxytryptamine 3 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50031934(6-(4-Methyl-piperazin-1-yl)-benzo[k]phenanthridine...)
Affinity DataKi:  920nMAssay Description:Binding affinity to 5-hydroxytryptamine 2A receptor from rat cortex assayed using [3H]ketanserin as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed