BDBM50031925 6-(4-Methyl-piperazin-1-yl)-7,8-dihydro-benzo[k]phenanthridine::CHEMBL417706

SMILES CN1CCN(CC1)c1nc2ccccc2c-2c1CCc1ccccc-21

InChI Key InChIKey=XZWNYGIFEAIRIB-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50031925   

Target5-hydroxytryptamine receptor 3A/3B(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50031925(6-(4-Methyl-piperazin-1-yl)-7,8-dihydro-benzo[k]ph...)
Affinity DataKi:  3.5nMAssay Description:Binding affinity for 5-hydroxytryptamine 3 receptor from rat cortex using [3H]BRL-43694 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50031925(6-(4-Methyl-piperazin-1-yl)-7,8-dihydro-benzo[k]ph...)
Affinity DataKi:  3.5nMAssay Description:Rat 5-hydroxytryptamine 3 receptor (5-HT3) antagonistMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50031925(6-(4-Methyl-piperazin-1-yl)-7,8-dihydro-benzo[k]ph...)
Affinity DataKi:  4.20nMAssay Description:Inhibition of [3H]granisetron binding to 5-hydroxytryptamine 3 receptor (5-HT 3 receptor) of rat cortex and hippocampus tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50031925(6-(4-Methyl-piperazin-1-yl)-7,8-dihydro-benzo[k]ph...)
Affinity DataKi:  400nMAssay Description:Binding affinity to 5-hydroxytryptamine 2A receptor from rat cortex assayed using [3H]ketanserin as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50031925(6-(4-Methyl-piperazin-1-yl)-7,8-dihydro-benzo[k]ph...)
Affinity DataKi:  6.60E+3nMAssay Description:Displacement of [3H]-GR113808 from 5-HT4 receptor of guinea pig striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50031925(6-(4-Methyl-piperazin-1-yl)-7,8-dihydro-benzo[k]ph...)
Affinity DataKi:  7.20E+3nMAssay Description:The compound was tested for their binding affinity towards 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed