BDBM50031924 CHEMBL304016::[2-(7,8-Dihydro-9-oxa-5-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-6-ylsulfanyl)-ethyl]-dimethyl-amine

SMILES CN(C)CCSc1nc2ccccc2c-2c1CCOc1ccccc-21

InChI Key InChIKey=RBSAECWKODMNRM-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50031924   

Target5-hydroxytryptamine receptor 3A/3B(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50031924([2-(7,8-Dihydro-9-oxa-5-aza-benzo[6,7]cyclohepta[1...)
Affinity DataKi:  46nMAssay Description:Binding affinity for 5-hydroxytryptamine 3 receptor from rat cortex using [3H]BRL-43694 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50031924([2-(7,8-Dihydro-9-oxa-5-aza-benzo[6,7]cyclohepta[1...)
Affinity DataKi:  46nMAssay Description:Rat 5-hydroxytryptamine 3 receptor (5-HT3) antagonistMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50031924([2-(7,8-Dihydro-9-oxa-5-aza-benzo[6,7]cyclohepta[1...)
Affinity DataKi:  1.30E+3nMAssay Description:The compound was tested for their binding affinity towards 5-hydroxytryptamine 1B receptor from rat striatum using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50031924([2-(7,8-Dihydro-9-oxa-5-aza-benzo[6,7]cyclohepta[1...)
Affinity DataKi:  2.80E+3nMAssay Description:Binding affinity to 5-hydroxytryptamine 2A receptor from rat cortex assayed using [3H]ketanserin as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed