BDBM50031791 (R)-3-((S)-1-Methylcarbamoyl-2-phenyl-ethylcarbamoyl)-heptanedioic acid 7-benzylamide 1-hydroxyamide::(R)-N5-benzyl-N1-hydroxy-N2-((S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl)pentane-1,2,5-tricarboxamide::CHEMBL430838

SMILES CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCC(=O)NCc1ccccc1)CC(=O)NO

InChI Key InChIKey=ALDQBTGTDJBFBQ-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50031791   

TargetNeutrophil collagenase(Human)
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50031791((R)-N5-benzyl-N1-hydroxy-N2-((S)-1-(methylamino)-1...)
Affinity DataKi:  30nMAssay Description:Inhibition of human neutrophil collagenase (HNC), MMP-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50031791((R)-N5-benzyl-N1-hydroxy-N2-((S)-1-(methylamino)-1...)
Affinity DataKi:  30nMAssay Description:Inhibition of human neutrophil collagenase, matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50031791((R)-N5-benzyl-N1-hydroxy-N2-((S)-1-(methylamino)-1...)
Affinity DataKi:  91nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50031791((R)-N5-benzyl-N1-hydroxy-N2-((S)-1-(methylamino)-1...)
Affinity DataKi:  92nMAssay Description:Inhibitory potency against human stromelysin, MMP-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50031791((R)-N5-benzyl-N1-hydroxy-N2-((S)-1-(methylamino)-1...)
Affinity DataKi:  92nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50031791((R)-N5-benzyl-N1-hydroxy-N2-((S)-1-(methylamino)-1...)
Affinity DataKi: <100nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3 (potent inhibitor)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50031791((R)-N5-benzyl-N1-hydroxy-N2-((S)-1-(methylamino)-1...)
Affinity DataKi:  9.60E+3nMAssay Description:Inhibitory potency against human fibroblast collagenase, MMP-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Sterling Winthrop Pharmaceuticals Research Division

Curated by ChEMBL
LigandPNGBDBM50031791((R)-N5-benzyl-N1-hydroxy-N2-((S)-1-(methylamino)-1...)
Affinity DataKi:  9.60E+3nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article