BDBM50031516 CHEMBL3359143

SMILES O=C(COc1ccc(cc1)C12CC3CC(CC(C3)C1)C2)Nc1cccc(c1)C(=O)c1ccc(OCC#C)cc1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50031516   

TargetHypoxia-inducible factor 1-alpha(Human)
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50031516(CHEMBL3359143)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of HIF-1alpha in human HCT116 cells incubated for 12 hrs under hypoxic conditions by Western blotting and HRE-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Human)
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50031516(CHEMBL3359143)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of MDH2 (unknown origin) pre-incubated for 1 hr followed by malate and NAD+ additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed