BDBM50031314 CHEMBL473326

SMILES Oc1nc(SCc2ccc(Cl)cc2)nc2CCCc12

InChI Key InChIKey=HKDAECHYHSQLRG-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50031314   

TargetCytochrome P450 3A4(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50031314(CHEMBL473326)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) using testosterone substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50031314(CHEMBL473326)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C8 (unknown origin) using amodiaquine substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50031314(CHEMBL473326)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of CYP1A2 (unknown origin) using tacrin substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50031314(CHEMBL473326)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2B6 (unknown origin) using bupropion substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50031314(CHEMBL473326)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin) using diclofenac substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50031314(CHEMBL473326)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin) using (S)-mephentoin substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50031314(CHEMBL473326)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin) using dextromethophan substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50031314(CHEMBL473326)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50031314(CHEMBL473326)
Affinity DataIC50: 3.40E+3nMAssay Description:Non-competitive inhibition of full-length recombinant human MMP-13 assessed as fTHP-15 substrate hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50031314(CHEMBL473326)
Affinity DataIC50: 700nMAssay Description:Inhibition of full-length recombinant human MMP-13 assessed as bovine type-2 collagen hydrolysis after 18 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed