BDBM50031296 7-[3-(4-Benzhydryl-piperidin-1-yl)-propyl]-1,3-dimethyl-3,7-dihydro-purine-2,6-dione; compound with (E)-but-2-enedioic acid::CHEMBL338611

SMILES Cn1c2ncn(CCCN3CCC(CC3)C(c3ccccc3)c3ccccc3)c2c(=O)n(C)c1=O

InChI Key InChIKey=YJWWBNSDIIFYRN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50031296   

TargetHistamine H1 receptor(Guinea pig)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50031296(7-[3-(4-Benzhydryl-piperidin-1-yl)-propyl]-1,3-dim...)
Affinity DataIC50: 44nMAssay Description:Compound is evaluated for in vitro receptor binding affinity against H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50031296(7-[3-(4-Benzhydryl-piperidin-1-yl)-propyl]-1,3-dim...)
Affinity DataIC50: 41nMAssay Description:Compound is evaluated for in vitro receptor binding affinity against Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50031296(7-[3-(4-Benzhydryl-piperidin-1-yl)-propyl]-1,3-dim...)
Affinity DataIC50: 46nMAssay Description:Compound is evaluated for in vitro receptor binding affinity against Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50031296(7-[3-(4-Benzhydryl-piperidin-1-yl)-propyl]-1,3-dim...)
Affinity DataIC50: 7.30E+3nMAssay Description:Compound is evaluated for in vitro receptor binding affinity against Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50031296(7-[3-(4-Benzhydryl-piperidin-1-yl)-propyl]-1,3-dim...)
Affinity DataIC50: 40nMAssay Description:Compound is evaluated for in vitro receptor binding affinity against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed