BDBM50031087 3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-5-thiocyanato-1H-pyrrole::CHEMBL126345

SMILES CS(=O)(=O)c1ccc(cc1)-c1[nH]c(SC#N)cc1-c1ccc(F)cc1

InChI Key InChIKey=YSDXJYVHLQVWIJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50031087   

TargetPhospholipase A2, major isoenzyme(Pig)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031087(3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-5...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity rat polymorphonuclear leukocyte phospholipase-A2 (PMN-PLA2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin-H2 D-isomerase(Bovine)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031087(3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-5...)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibitory activity against bovine seminal vesicle prostaglandin synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, major isoenzyme(Pig)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031087(3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-5...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibitory activity porcine pancreatic phospholipase-A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031087(3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-5...)
Affinity DataIC50: 80nMAssay Description:Inhibitory activity against rat basophilic leukemia 5-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031087(3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-5...)
Affinity DataIC50: 7.20E+4nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 2 from humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50031087(3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-5...)
Affinity DataIC50: 2.19E+5nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 1 from ovineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed