BDBM50030879 CHEMBL3356126

SMILES CC(=O)c1ccc(cc1)N1CCN(CC1)C(=O)CN1CC[C@H](C1)C(=O)Nc1cc(Cl)c(O)c(Cl)c1

InChI Key InChIKey=MBCGDEROXRLCKP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50030879   

TargetMitogen-activated protein kinase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030879(CHEMBL3356126)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of phosphorylated ERK2 (unknown origin) by temperature dependent fluorescence (TdF) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030879(CHEMBL3356126)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of inactive ERK2 (unknown origin) coupled with human MEK1 using IMAP peptide substrate after 30 mins by coupled ERK2 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030879(CHEMBL3356126)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of unphosphorylated ERK2 (unknown origin) by temperature dependent fluorescence (TdF) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed