BDBM50030830 CHEMBL3342570

SMILES Cc1cc(Br)cc2C=C(C(Oc12)C(F)(F)F)C(O)=O

InChI Key InChIKey=ILHUJLLYTPMLPK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50030830   

TargetProstaglandin G/H synthase 2(Human)
Institutes of Biomedicine and Health

Curated by ChEMBL
LigandPNGBDBM50030830(CHEMBL3342570)
Affinity DataIC50: 28nMAssay Description:Inhibition of human recombinant COX2 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Institutes of Biomedicine and Health

Curated by ChEMBL
LigandPNGBDBM50030830(CHEMBL3342570)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant COX1 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Institutes of Biomedicine and Health

Curated by ChEMBL
LigandPNGBDBM50030830(CHEMBL3342570)
Affinity DataIC50: 39nMAssay Description:Inhibition of human recombinant COX2 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed