BDBM50030826 CHEMBL1290565

SMILES CCc1cc(OC(F)(F)F)cc2C=C(C(Oc12)C(F)(F)F)C(O)=O

InChI Key InChIKey=DNSZVRYSOQVHKS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50030826   

TargetProstaglandin G/H synthase 2(Human)
Institutes of Biomedicine and Health

Curated by ChEMBL
LigandPNGBDBM50030826(CHEMBL1290565)
Affinity DataIC50: 49nMAssay Description:Inhibition of human recombinant COX2 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Institutes of Biomedicine and Health

Curated by ChEMBL
LigandPNGBDBM50030826(CHEMBL1290565)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant COX1 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Institutes of Biomedicine and Health

Curated by ChEMBL
LigandPNGBDBM50030826(CHEMBL1290565)
Affinity DataIC50: 61nMAssay Description:Inhibition of human recombinant COX2 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed