BDBM50030825 CHEMBL3342569

SMILES Cc1c(Br)c(C)c2C=C(C(Oc2c1Br)C(F)(F)F)C(O)=O

InChI Key InChIKey=MHGZSKAUAPUHJN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50030825   

TargetProstaglandin G/H synthase 2(Human)
Institutes of Biomedicine and Health

Curated by ChEMBL
LigandPNGBDBM50030825(CHEMBL3342569)
Affinity DataIC50: 69nMAssay Description:Inhibition of human recombinant COX2 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Institutes of Biomedicine and Health

Curated by ChEMBL
LigandPNGBDBM50030825(CHEMBL3342569)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant COX1 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Institutes of Biomedicine and Health

Curated by ChEMBL
LigandPNGBDBM50030825(CHEMBL3342569)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant COX1 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Institutes of Biomedicine and Health

Curated by ChEMBL
LigandPNGBDBM50030825(CHEMBL3342569)
Affinity DataIC50: 84nMAssay Description:Inhibition of human recombinant COX2 pre-incubated for 15 mins before fluorometric substrate addition by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed