BDBM50030818 (S)-2-(4-{[(2,4-Diamino-furo[2,3-d]pyrimidin-5-ylmethyl)-amino]-methyl}-benzoylamino)-pentanedioic acid::2-(4-{[(2,4-Diamino-furo[2,3-d]pyrimidin-5-ylmethyl)-amino]-methyl}-benzoylamino)-pentanedioic acid::CHEMBL106699

SMILES Nc1nc(N)c2c(CNCc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)coc2n1

InChI Key InChIKey=KJKYBYBHOJCFEZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50030818   

TargetThymidylate synthase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030818((S)-2-(4-{[(2,4-Diamino-furo[2,3-d]pyrimidin-5-ylm...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory concentration against Lactobacillus casei TS (Thymidylate synthase).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030818((S)-2-(4-{[(2,4-Diamino-furo[2,3-d]pyrimidin-5-ylm...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory concentration against recombinant human DHFR(Dihydro folate reductase).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030818((S)-2-(4-{[(2,4-Diamino-furo[2,3-d]pyrimidin-5-ylm...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory concentration against Lactobacillus casei TS (Thymidylate synthase).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030818((S)-2-(4-{[(2,4-Diamino-furo[2,3-d]pyrimidin-5-ylm...)
Affinity DataIC50: 3.05E+4nMAssay Description:Inhibitory concentration against CCRF-CEM leukemic cell DHFR(Dihydro folate reductase).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030818((S)-2-(4-{[(2,4-Diamino-furo[2,3-d]pyrimidin-5-ylm...)
Affinity DataIC50: 2.00E+5nMAssay Description:inhibitory concentration against Lactobacillus casei DHFR(Dihydro folate reductase).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50030818((S)-2-(4-{[(2,4-Diamino-furo[2,3-d]pyrimidin-5-ylm...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed