BDBM50030510 CHEMBL299668::[1-Benzyl-7-chloro-1H-quinolin-(4E)-ylidene]-pentyl-amine

SMILES CCCCC\N=c1/ccn(Cc2ccccc2)c2cc(Cl)ccc12

InChI Key InChIKey=QCZNJMNZZBRTHD-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50030510   

TargetPotassium voltage-gated channel subfamily A member 3(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50030510([1-Benzyl-7-chloro-1H-quinolin-(4E)-ylidene]-penty...)
Affinity DataIC50: 65nMAssay Description:Concentration inhibiting [125I]ChTX (charybdotoxin) binding to N-type potassium channel.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Sanofi Winthrop

Curated by ChEMBL
LigandPNGBDBM50030510([1-Benzyl-7-chloro-1H-quinolin-(4E)-ylidene]-penty...)
Affinity DataIC50: 250nMAssay Description:Inhibition of outward potassium currents (IKn) in human T-lymphocyte N-type potassium channels.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Human)
Institute of Nuclear Medicine

Curated by ChEMBL
LigandPNGBDBM50030510([1-Benzyl-7-chloro-1H-quinolin-(4E)-ylidene]-penty...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human voltage-gated sodium channel subunit alpha Nav1.2 expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Institute of Nuclear Medicine

Curated by ChEMBL
LigandPNGBDBM50030510([1-Benzyl-7-chloro-1H-quinolin-(4E)-ylidene]-penty...)
Affinity DataKi:  9nMAssay Description:Inhibition of rat brain voltage-gated sodium channel subunit alpha Nav1.2-mediated current expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed