BDBM50030432 CHEMBL305608::N-[(S)-1-[(3,5-Dimethyl-benzyl)-methyl-carbamoyl]-2-(1H-indol-3-yl)-ethyl]-benzamide

SMILES CN(Cc1cc(C)cc(C)c1)C(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)c1ccccc1

InChI Key InChIKey=KWYBCHYLXFETGY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50030432   

TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030432(N-[(S)-1-[(3,5-Dimethyl-benzyl)-methyl-carbamoyl]-...)
Affinity DataIC50: 1.03E+3nMAssay Description:Binding affinity against human Tachykinin receptor 1 expressed in CHO cells was measured by its ability to displace [125I]- Tyr-8 substance P.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030432(N-[(S)-1-[(3,5-Dimethyl-benzyl)-methyl-carbamoyl]-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of cloned human NK2 (Neurokinin 2) receptor, stably expressed in chinese hamster ovary (CHO) cells was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030432(N-[(S)-1-[(3,5-Dimethyl-benzyl)-methyl-carbamoyl]-...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of cloned human NK1 (Neurokinin 1) receptor, stably expressed in chinese hamster ovary (CHO) cells was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed