BDBM50030106 CHEMBL3343535

SMILES NC(=O)c1cncc(Oc2ccc3c(NC(=O)c4cccc(c4)[N+]([O-])=O)cccc3c2)c1

InChI Key InChIKey=XDLNITCMISPVNF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50030106   

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50030106(CHEMBL3343535)
Affinity DataIC50: 811nMAssay Description:Inhibition of full length human SIRT2 expressed in Escherichia coli BL21 (DE3) cells using fluorogenic 7-amino-4-methylcoumarin (AMC)-labeled peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50030106(CHEMBL3343535)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of full length human SIRT1 expressed in Escherichia coli BL21 (DE3) cells using fluorogenic 7-amino-4-methylcoumarin (AMC)-labeled peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50030106(CHEMBL3343535)
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of catalytically active human SIRT3 (102 to 399 amino acids) expressed in Escherichia coli BL21 (DE3) cells using fluorogenic 7-amino-4-me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed