BDBM50030105 CHEMBL3343534

SMILES Cc1ccc(cc1)C(=O)Nc1cccc2cc(Oc3cncc(c3)C(N)=O)ccc12

InChI Key InChIKey=SETQPKYYWQWFIA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50030105   

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50030105(CHEMBL3343534)
Affinity DataIC50: 489nMAssay Description:Inhibition of full length human SIRT2 expressed in Escherichia coli BL21 (DE3) cells using fluorogenic 7-amino-4-methylcoumarin (AMC)-labeled peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50030105(CHEMBL3343534)
Affinity DataIC50: 3.82E+3nMAssay Description:Inhibition of full length human SIRT1 expressed in Escherichia coli BL21 (DE3) cells using fluorogenic 7-amino-4-methylcoumarin (AMC)-labeled peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50030105(CHEMBL3343534)
Affinity DataIC50: 2.29E+4nMAssay Description:Inhibition of catalytically active human SIRT3 (102 to 399 amino acids) expressed in Escherichia coli BL21 (DE3) cells using fluorogenic 7-amino-4-me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed