BDBM50029843 (2R,3R)-2-Benzhydryl-3-(3,5-bis-trifluoromethyl-benzyloxy)-1-aza-bicyclo[2.2.2]octane::CHEMBL297068

SMILES FC(F)(F)c1cc(CO[C@@H]2C3CCN(CC3)[C@@H]2C(c2ccccc2)c2ccccc2)cc(c1)C(F)(F)F

InChI Key InChIKey=NNQQINUYFDRYPI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50029843   

TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029843((2R,3R)-2-Benzhydryl-3-(3,5-bis-trifluoromethyl-be...)
Affinity DataIC50: 300nMAssay Description:Inhibition of binding of [125I]SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029843((2R,3R)-2-Benzhydryl-3-(3,5-bis-trifluoromethyl-be...)
Affinity DataIC50: 570nMAssay Description:Tested for binding affinity by measuring displacement of [125I]SP from human NK-1 receptor in CHO CellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029843((2R,3R)-2-Benzhydryl-3-(3,5-bis-trifluoromethyl-be...)
Affinity DataIC50: 575nMAssay Description:Binding affinity was measured against the Tachykinin receptor 1 in CHO-expressed hNK1 using [125I]SP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed