BDBM50029790 5-(3-Methoxy-phenyl)-2-methyl-8-[1-phenyl-meth-(E)-ylidene]-2-aza-bicyclo[3.3.1]nonan-7-one::CHEMBL109124

SMILES COc1cccc(c1)C12CCN(C)C(C1)C(=Cc1ccccc1)C(=O)C2

InChI Key InChIKey=QZJJWXHOVZHRTH-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50029790   

TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50029790(5-(3-Methoxy-phenyl)-2-methyl-8-[1-phenyl-meth-(E)...)
Affinity DataKi:  138nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50029790(5-(3-Methoxy-phenyl)-2-methyl-8-[1-phenyl-meth-(E)...)
Affinity DataKi:  138nMAssay Description:Ability to inhibit [3H](+)-pentazocine binding to guinea pig brain Sigma receptor type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50029790(5-(3-Methoxy-phenyl)-2-methyl-8-[1-phenyl-meth-(E)...)
Affinity DataKi:  138nMAssay Description:Ability to inhibit [3H](+)-pentazocine binding to guinea pig brain Sigma receptor type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50029790(5-(3-Methoxy-phenyl)-2-methyl-8-[1-phenyl-meth-(E)...)
Affinity DataKi: >250nMAssay Description:Ability to inhibit [3H]DAMGO binding to rat brain Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50029790(5-(3-Methoxy-phenyl)-2-methyl-8-[1-phenyl-meth-(E)...)
Affinity DataKi: >250nMAssay Description:Ability to inhibit [3H]DAMGO binding to rat brain Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50029790(5-(3-Methoxy-phenyl)-2-methyl-8-[1-phenyl-meth-(E)...)
Affinity DataKi: >500nMAssay Description:Ability to inhibit [3H]DADLE binding to rat brain delta receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50029790(5-(3-Methoxy-phenyl)-2-methyl-8-[1-phenyl-meth-(E)...)
Affinity DataKi: >500nMAssay Description:Ability to inhibit [3H]DADLE binding to rat brain delta receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50029790(5-(3-Methoxy-phenyl)-2-methyl-8-[1-phenyl-meth-(E)...)
Affinity DataKi: >1.00E+3nMAssay Description:Ability to inhibit [3H]U-69593 binding to guinea pig Opioid receptor kappa 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed