BDBM50029767 5-{4-chloro-3-[(1E)-3-ethyltriaz-1-enyl]phenyl}-6-ethylpyrimidine-2,4-diamine::CHEMBL357573

SMILES CCN=NNc1cc(ccc1Cl)-c1c(N)nc(N)nc1CC

InChI Key InChIKey=CPYNKCXEGCQNNF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50029767   

TargetDihydrofolate reductase(Pneumocystis carinii)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50029767(5-{4-chloro-3-[(1E)-3-ethyltriaz-1-enyl]phenyl}-6-...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibitory activity of Pneumocystis carinii growth culture against dihydrofolate reductase. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50029767(5-{4-chloro-3-[(1E)-3-ethyltriaz-1-enyl]phenyl}-6-...)
Affinity DataIC50: 1.89E+4nMAssay Description:Inhibitory activity against dihydrofolate reductase in rat. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50029767(5-{4-chloro-3-[(1E)-3-ethyltriaz-1-enyl]phenyl}-6-...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibitory activity was determined against dihydrofolate reductase in Pneumocystis carinii. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed