BDBM50029765 2-Chloro-5-(2,4-diamino-6-ethyl-pyrimidin-5-yl)-benzenediazonium::CHEMBL142345::CHEMBL57222

SMILES CCc1nc(N)nc(N)c1-c1ccc(Cl)c(c1)[N+]#N

InChI Key InChIKey=JQBXDBXIJYZMGS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50029765   

TargetDihydrofolate reductase(Pneumocystis carinii)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50029765(CHEMBL142345 | CHEMBL57222 | 2-Chloro-5-(2,4-diami...)
Affinity DataIC50: 190nMAssay Description:Inhibitory activity was determined against dihydrofolate reductase in Pneumocystis carinii. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50029765(CHEMBL142345 | CHEMBL57222 | 2-Chloro-5-(2,4-diami...)
Affinity DataIC50: 190nMAssay Description:In vitro inhibitory concentration against Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50029765(CHEMBL142345 | CHEMBL57222 | 2-Chloro-5-(2,4-diami...)
Affinity DataIC50: 23nMAssay Description:Inhibitory concentration against Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50029765(CHEMBL142345 | CHEMBL57222 | 2-Chloro-5-(2,4-diami...)
Affinity DataIC50: 32nMAssay Description:In vitro inhibitory concentration against rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed