BDBM50029744 CHEMBL3353417

SMILES COc1cccc(CCn2c3CCCC(=O)c3c3C(=O)c4ccccc4-c23)c1

InChI Key InChIKey=LOIVDCFVCNLNCO-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50029744   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Bmssi Umr 5086 Cnrs/Universit£

Curated by ChEMBL
LigandPNGBDBM50029744(CHEMBL3353417)
Affinity DataIC50: 310nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in HEK293 cells assessed as reduction in mitoxantrone efflux after 30 mins by FACS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Bmssi Umr 5086 Cnrs/Universit£

Curated by ChEMBL
LigandPNGBDBM50029744(CHEMBL3353417)
Affinity DataEC50:  310nMAssay Description:Inhibition of ABCG2 (unknown origin)-mediated mitoxantrone effluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed