BDBM50029729 3'-tert-Butyl-5'-hydroxy-biphenyl-4-carboxylic acid benzylamide::CHEMBL143160

SMILES CC(C)(C)c1cc(O)cc(c1)-c1ccc(cc1)C(=O)NCc1ccccc1

InChI Key InChIKey=GYILJKVKRPIVKD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50029729   

TargetEpidermal growth factor receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50029729(3'-tert-Butyl-5'-hydroxy-biphenyl-4-carboxylic aci...)
Affinity DataIC50: 5.40E+3nMAssay Description:In vitro inhibition of EGF-stimulated DNA synthesis of ER 22 cells by following the incorporation of methyl-[3H]thymidine.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50029729(3'-tert-Butyl-5'-hydroxy-biphenyl-4-carboxylic aci...)
Affinity DataIC50: 5.00E+3nMAssay Description:In vitro inhibition of intrinsic tyrosine protein kinase activity of the Epidermal growth factor receptor using tripeptide RR-SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed