BDBM50029511 CHEMBL104472::tert-butyloxy carbonyl-D-Phe-pro-Arg-H::{(R)-1-Benzyl-2-[(S)-2-((S)-1-formyl-4-guanidino-butylcarbamoyl)-pyrrolidin-1-yl]-2-oxo-ethyl}-carbamic acid tert-butyl ester

SMILES CC(C)(C)OC(=O)N[C@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C=O

InChI Key InChIKey=JDXUSWQJCGTBLN-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50029511   

TargetTissue-type plasminogen activator(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029511({(R)-1-Benzyl-2-[(S)-2-((S)-1-formyl-4-guanidino-b...)
Affinity DataIC50: 950nMAssay Description:In vitro Enzyme Inhibitory activity against t-PA(Tissue plasminogen activator).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029511({(R)-1-Benzyl-2-[(S)-2-((S)-1-formyl-4-guanidino-b...)
Affinity DataIC50: 14nMAssay Description:In vitro Enzyme Inhibitory activity measured against TrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029511({(R)-1-Benzyl-2-[(S)-2-((S)-1-formyl-4-guanidino-b...)
Affinity DataIC50: 45nMAssay Description:In vitro Enzyme Inhibitory activity measured against ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Bovine)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029511({(R)-1-Benzyl-2-[(S)-2-((S)-1-formyl-4-guanidino-b...)
Affinity DataIC50: 1.60E+3nMAssay Description:In vitro Enzyme Inhibitory activity measured against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029511({(R)-1-Benzyl-2-[(S)-2-((S)-1-formyl-4-guanidino-b...)
Affinity DataIC50: 190nMAssay Description:In vitro Enzyme Inhibitory activity measured against PlasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50029511({(R)-1-Benzyl-2-[(S)-2-((S)-1-formyl-4-guanidino-b...)
Affinity DataIC50: 45nMAssay Description:In vitro inhibitory activity against human ProthrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed