BDBM50029504 CHEMBL139490::{(S)-1-Benzyl-2-[(S)-2-((S)-1-formyl-4-guanidino-butylcarbamoyl)-piperidin-1-yl]-2-oxo-ethyl}-carbamic acid tert-butyl ester

SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C=O

InChI Key InChIKey=VRVVBGSOZKAWJG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50029504   

TargetTissue-type plasminogen activator(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029504({(S)-1-Benzyl-2-[(S)-2-((S)-1-formyl-4-guanidino-b...)
Affinity DataIC50: 4.80E+4nMAssay Description:In vitro Enzyme Inhibitory activity against t-PA(Tissue plasminogen activator).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029504({(S)-1-Benzyl-2-[(S)-2-((S)-1-formyl-4-guanidino-b...)
Affinity DataIC50: 8.10E+3nMAssay Description:In vitro Enzyme Inhibitory activity measured against PlasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029504({(S)-1-Benzyl-2-[(S)-2-((S)-1-formyl-4-guanidino-b...)
Affinity DataIC50: 720nMAssay Description:In vitro Enzyme Inhibitory activity measured against TrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Bovine)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029504({(S)-1-Benzyl-2-[(S)-2-((S)-1-formyl-4-guanidino-b...)
Affinity DataIC50: 3.20E+4nMAssay Description:In vitro Enzyme Inhibitory activity measured against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Bovine)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029504({(S)-1-Benzyl-2-[(S)-2-((S)-1-formyl-4-guanidino-b...)
Affinity DataIC50: 1.70E+3nMAssay Description:In vitro Enzyme Inhibitory activity measured against ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed