BDBM50029353 CHEMBL414165::[(5S,8S,11R,14R,16aR)-8-(1H-Indol-3-ylmethyl)-11-isobutyl-4,7,10,13,16-pentaoxo-14-thiophen-2-yl-hexadecahydro-3a,6,9,12,15-pentaaza-cyclopentacyclopentadecen-5-yl]-acetic acid

SMILES CC(C)C[C@H]1NC(=O)[C@@H](NC(=O)[C@H]2CCCN2C(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O)c1cccs1

InChI Key InChIKey=KXUDUVUGZWJNHV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50029353   

TargetEndothelin receptor type B(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50029353([(5S,8S,11R,14R,16aR)-8-(1H-Indol-3-ylmethyl)-11-i...)
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibitory effect against Human Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Pig)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50029353([(5S,8S,11R,14R,16aR)-8-(1H-Indol-3-ylmethyl)-11-i...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibitory effect against porcine Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Pig)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50029353([(5S,8S,11R,14R,16aR)-8-(1H-Indol-3-ylmethyl)-11-i...)
Affinity DataIC50: 3nMAssay Description:Inhibitory effect against porcine ET-A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50029353([(5S,8S,11R,14R,16aR)-8-(1H-Indol-3-ylmethyl)-11-i...)
Affinity DataIC50: 1.20nMAssay Description:Inhibitory effect against Human ET-A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Pig)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50029353([(5S,8S,11R,14R,16aR)-8-(1H-Indol-3-ylmethyl)-11-i...)
Affinity DataIC50: 3nMAssay Description:The compound was tested for binding inhibitory activity against Endothelin A receptor from porcine aortic smooth muscle membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed