BDBM50029209 (E)-3-(3,4-Dihydroxy-phenyl)-acrylic acid methyl ester::(E)-methyl 3-(3,4-dihydroxyphenyl)acrylate::3-(3,4-Dihydroxy-phenyl)-acrylic acid methyl ester::CHEMBL17001::METHYLCAFFEATE::Methyl 1-(3',4'-dihydroxyphenyl)propenate::Methyl caffeate::methyl 3-(3,4-dihydroxyphenyl)acrylate

SMILES COC(=O)\C=C\c1ccc(O)c(O)c1

InChI Key InChIKey=OCNYGKNIVPVPPX-UHFFFAOYSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50029209   

TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50029209(CHEMBL17001 | (E)-3-(3,4-Dihydroxy-phenyl)-acrylic...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against HIV-1 integrase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransthyretin(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50029209(CHEMBL17001 | (E)-3-(3,4-Dihydroxy-phenyl)-acrylic...)
Affinity DataEC50:  6.70E+4nMAssay Description:Inhibition of TTR V30M mutant (unknown origin) expressed in Escherichia coli assessed as inhibition of amyloid fibril formation by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
Target3-oxoacyl-ACP synthase(Pseudomonas aeruginosa)
Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50029209(CHEMBL17001 | (E)-3-(3,4-Dihydroxy-phenyl)-acrylic...)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of Pseudomonas aeruginosa recombinant PqsD expressed in Escherichia coli BL21 (lambdaDE3) using ACoA/beta-ketodecanoic acid as substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50029209(CHEMBL17001 | (E)-3-(3,4-Dihydroxy-phenyl)-acrylic...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against HIV-1 Integrase (HIV-1-IN)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Muroran Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50029209(CHEMBL17001 | (E)-3-(3,4-Dihydroxy-phenyl)-acrylic...)
Affinity DataEC50:  6.77E+4nMAssay Description:Inhibition of QD-labeled amyloid beta (1 to 42) (unknown origin) aggregation after 24 hrs by inverted fluorescence microscopic methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50029209(CHEMBL17001 | (E)-3-(3,4-Dihydroxy-phenyl)-acrylic...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HIV1 integrase by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed