BDBM50029201 6,7-Dihydroxy-isoquinoline-3-carboxylic acid benzylamide::CHEMBL296582

SMILES Oc1cc2cnc(cc2cc1O)C(=O)NCc1ccccc1

InChI Key InChIKey=CYMDDJODSVMYBQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50029201   

TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50029201(6,7-Dihydroxy-isoquinoline-3-carboxylic acid benzy...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against HIV-1 integrase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50029201(6,7-Dihydroxy-isoquinoline-3-carboxylic acid benzy...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetTyrosine-protein kinase Lck(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50029201(6,7-Dihydroxy-isoquinoline-3-carboxylic acid benzy...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of p56 lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50029201(6,7-Dihydroxy-isoquinoline-3-carboxylic acid benzy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against HIV-1 Integrase (HIV-1-IN)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed