BDBM50029109 CHEMBL3361419

SMILES COc1cc(NC2(CNC(=O)CNC(N)=N)CCN(Cc3ccccc3)CC2)cc(OC)c1

InChI Key InChIKey=ADVZHMYYGIKXKT-UHFFFAOYSA-N

Data  5 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50029109   

TargetNeuropeptide FF receptor 1(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50029109(CHEMBL3361419)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human NPFF1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced intracellular cAMP accumulation by liquid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 1(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50029109(CHEMBL3361419)
Affinity DataKi:  114nMAssay Description:Displacement of [3H]NPVF from human NPFF1 receptor expressed in CHO cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50029109(CHEMBL3361419)
Affinity DataKi:  688nMAssay Description:Displacement of [3H]DAMGO from human MOR expressed in HEK293 cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50029109(CHEMBL3361419)
Affinity DataKi:  987nMAssay Description:Displacement of [3H]EYF from human NPFF2 receptor expressed in CHO cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50029109(CHEMBL3361419)
Affinity DataKi:  3.68E+3nMAssay Description:Displacement of [3H]U-69593 from human KOR expressed in HEK293 cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50029109(CHEMBL3361419)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]DPDPE from human DOR expressed in HEK293 cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed