BDBM50028887 CHEMBL3359635

SMILES [O-][N+](=O)c1cc(Cl)ccc1Sc1ccncc1

InChI Key InChIKey=VGQCOWWMSJJMKU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50028887   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Centro De Investigaciones Biol�Gicas (Csic)

Curated by ChEMBL
LigandPNGBDBM50028887(CHEMBL3359635)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human recombinant PDE4B2 assessed after 60 mins by IMAP fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2016
Entry Details Article
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Centro De Investigaciones Biol�Gicas (Csic)

Curated by ChEMBL
LigandPNGBDBM50028887(CHEMBL3359635)
Affinity DataIC50: 720nMAssay Description:Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2016
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Human)
Centro De Investigaciones Biol�Gicas (Csic)

Curated by ChEMBL
LigandPNGBDBM50028887(CHEMBL3359635)
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of human recombinant PDE7B assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2016
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Centro De Investigaciones Biol�Gicas (Csic)

Curated by ChEMBL
LigandPNGBDBM50028887(CHEMBL3359635)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant PDE4D3 assessed after 60 mins by IMAP fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2016
Entry Details Article
PubMed