BDBM500287 US11021475, Example 51

SMILES CNC(=O)c1nnc(Nc2cc(COC)ccn2)cc1Nc1ccccc1S(C)(=O)=O

InChI Key InChIKey=XAURTEYGQDGEPF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 500287   

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM500287(US11021475, Example 51)
Affinity DataEC50:  7.19nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
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