BDBM500284 US11021475, Example 5

SMILES CS(=O)(=O)c1ccccc1Nc1cc(Nc2ccc(F)cn2)nnc1C(=O)NC1CC1

InChI Key InChIKey=XNRAGLFURZEUPQ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 500284   

TargetNon-receptor tyrosine-protein kinase TYK2 [575-869](Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM500284(US11021475, Example 5)
Affinity DataEC50:  410nMAssay Description:The probe displacement assay is conducted as follows: In a 385 well plate, test compounds along with recombinantly expressed His-tagged protein corre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
Go to US Patent