BDBM50027665 (E)-1-(2,4-dihydroxyphenyl)-3-(2-allyloxyphenyl)-2-propen-1-one (5)::CHEMBL3357534

SMILES Oc1ccc(C(=O)\C=C\c2ccccc2OCC=C)c(O)c1

InChI Key InChIKey=JOUAFGREHOHSPE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50027665   

TargetBeta-secretase 1(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

LigandPNGBDBM50027665(CHEMBL3357534 | (E)-1-(2,4-dihydroxyphenyl)-3-(2-a...)
Affinity DataIC50: 6.00E+4nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2017
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
University of Hawaii At Hilo

Curated by ChEMBL
LigandPNGBDBM50027665(CHEMBL3357534 | (E)-1-(2,4-dihydroxyphenyl)-3-(2-a...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as supercoiled plasmid DNA formation after 30 mins by electrophoretic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed