BDBM50027306 1H-Indole-5-carboxamidine::CHEMBL26490

SMILES NC(=N)c1ccc2[nH]ccc2c1

InChI Key InChIKey=DAUPWONEWDTPEP-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50027306   

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50027306(1H-Indole-5-carboxamidine | CHEMBL26490)
Affinity DataIC50: 2.20E+4nMAssay Description:Compound was evaluated for inhibition of human alpha-thrombin catalytic activity.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetProthrombin(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50027306(1H-Indole-5-carboxamidine | CHEMBL26490)
Affinity DataKi:  7.68E+3nMAssay Description:Inhibition constant against bovine thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50027306(1H-Indole-5-carboxamidine | CHEMBL26490)
Affinity DataKi:  2.91E+4nMAssay Description:Inhibition constant against bovine trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50027306(1H-Indole-5-carboxamidine | CHEMBL26490)
Affinity DataKi:  1.12E+5nMAssay Description:Inhibition constant against human plasminogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50027306(1H-Indole-5-carboxamidine | CHEMBL26490)
Affinity DataKi:  1.31E+5nMAssay Description:Inhibition constant against Urokinase; IrregularMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50027306(1H-Indole-5-carboxamidine | CHEMBL26490)
Affinity DataKi:  5.00E+5nMAssay Description:Inhibition of human recombinant hepsin by fluorescence based assay using 65 uM BOC-Gln-Arg-Arg -AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed