BDBM50027251 CHEMBL2113310

SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@@]51CC[C@]2(OC)[C@@H](CNC\C=C\c2ccc(Cl)cc2)C1)ccc3OC

InChI Key

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50027251   

TargetMu-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50027251(CHEMBL2113310)
Affinity DataEC50:  149nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50027251(CHEMBL2113310)
Affinity DataEC50:  233nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50027251(CHEMBL2113310)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]DAMGO from human cloned mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50027251(CHEMBL2113310)
Affinity DataKi:  68nMAssay Description:Displacement of [3H]U-69593 from human cloned kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50027251(CHEMBL2113310)
Affinity DataKi:  742nMAssay Description:Displacement of [3H]DPDPE from human cloned delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed