BDBM50027131 CHEMBL2145454

SMILES CC(C)(C)NC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(F)cc1)NC(=O)[C@@H]1CN(CC(F)F)CCN1)C1CCCCC1

InChI Key InChIKey=HNZYHHSJGTZICV-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50027131   

TargetMelanocortin receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50027131(CHEMBL2145454)
Affinity DataEC50:  510nMAssay Description:Effective concentration towards human melanocortin-5 receptor mediated cAMP accumulation in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50027131(CHEMBL2145454)
Affinity DataEC50:  52nMAssay Description:Effective concentration towards human melanocortin-4 receptor mediated cAMP accumulation in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50027131(CHEMBL2145454)
Affinity DataIC50: 13nMAssay Description:Concentration for 50% inhibition of human melanocortin-4 receptor expressed in CHO cells using [125I]NDP-alpha-MSH as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed