BDBM50027035 3-[(4,5-Dihydro-1H-imidazol-2-ylmethyl)-amino]-phenol::CHEMBL51479

SMILES Oc1cccc(NCC2=NCCN2)c1

InChI Key InChIKey=UDIUQEYOECRTHA-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50027035   

LigandPNGBDBM50027035(3-[(4,5-Dihydro-1H-imidazol-2-ylmethyl)-amino]-phe...)
Affinity DataEC50:  74nMAssay Description:Agonistic activity against alpha alpha-2 adrenergic receptor in isolated, field -simulated vas deferens from ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50027035(3-[(4,5-Dihydro-1H-imidazol-2-ylmethyl)-amino]-phe...)
Affinity DataEC50:  61nMAssay Description:Agonist activity against alpha-1 adrenergic receptor from rat vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50027035(3-[(4,5-Dihydro-1H-imidazol-2-ylmethyl)-amino]-phe...)
Affinity DataKi:  7.10nMAssay Description:Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]clonidine as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50027035(3-[(4,5-Dihydro-1H-imidazol-2-ylmethyl)-amino]-phe...)
Affinity DataKi:  380nMAssay Description:Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]prazosin as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed