BDBM50026960 (trans) 2-{4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethanol; Dihydrochloride::2-{4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethanol::CHEMBL422067

SMILES OCCN1CCN(CC1)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1

InChI Key InChIKey=WVMPJMHWCBRDFH-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50026960   

TargetD(1A) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50026960(2-{4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-pip...)
Affinity DataIC50: 8.30nMAssay Description:The compound was tested for the binding affinity against Dopamine receptor D1 activity is expressed as IC50 values.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50026960(2-{4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-pip...)
Affinity DataIC50: 20nMAssay Description:Binding affinity against dopamine receptor D2 More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50026960(2-{4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-pip...)
Affinity DataIC50: 20nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptors in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
LigandPNGBDBM50026960(2-{4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-pip...)
Affinity DataIC50: 13nMAssay Description:Ability to displace [3H]haloperidol from rat striatal membranes, in order to measure its intrinsic affinity for the dopamine (DA) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50026960(2-{4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-pip...)
Affinity DataIC50: 26nMAssay Description:Displacement of [3H]prazosin from alpha-1 adrenoceptors in whole rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50026960(2-{4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-pip...)
Affinity DataIC50: 2.60nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed