BDBM50026939 8-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL440302

SMILES COc1ccccc1N1CCN(CCCN2C(=O)CC3(CCCC3)CC2=O)CC1

InChI Key InChIKey=NGKZRYQYMHFGRK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50026939   

Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50026939(8-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}...)
Affinity DataIC50: 80nMAssay Description:Compound was evaluated for its ability to displace [3H]8-OH-DPAT from serotonin 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50026939(8-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}...)
Affinity DataIC50: 430nMAssay Description:Inhibition of [3H]spiperone binding to dopamine receptor from rat corpus striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2018
Entry Details Article
PubMed
LigandPNGBDBM50026939(8-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}...)
Affinity DataIC50: 19nMAssay Description:Inhibition of [3H]WB-4101 binding to alpha-1-adrenergic receptor from rat cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2018
Entry Details Article
PubMed