BDBM50026778 2-(2,5-Dimethoxy-phenyl)-ethylamine::2-(2,5-dimethoxyphenyl)ethylamine::CHEMBL287047

SMILES COc1ccc(OC)c(CCN)c1

InChI Key InChIKey=WNCUVUUEJZEATP-UHFFFAOYSA-N

Data  5 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50026778   

TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50026778(2-(2,5-Dimethoxy-phenyl)-ethylamine | 2-(2,5-dimet...)
Affinity DataEC50:  2.01E+3nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50026778(2-(2,5-Dimethoxy-phenyl)-ethylamine | 2-(2,5-dimet...)
Affinity DataEC50:  1.10E+4nMAssay Description:Alpha-1 adrenergic receptor agonist activity in rabbit ear arteryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50026778(2-(2,5-Dimethoxy-phenyl)-ethylamine | 2-(2,5-dimet...)
Affinity DataKi:  2.82E+3nMAssay Description:Binding affinity against rat 5-hydroxytryptamine 2A receptor using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50026778(2-(2,5-Dimethoxy-phenyl)-ethylamine | 2-(2,5-dimet...)
Affinity DataKi:  2.82E+3nMAssay Description:Displacement of [3H]ketanserin from rat 5HT2A expressed in mouse NIH/3T3 cell membranes after 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50026778(2-(2,5-Dimethoxy-phenyl)-ethylamine | 2-(2,5-dimet...)
Affinity DataKi:  3.00E+3nMAssay Description:Displacement of [3H]ketanserin from NIH3T3 cells stably expressing rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50026778(2-(2,5-Dimethoxy-phenyl)-ethylamine | 2-(2,5-dimet...)
Affinity DataKi:  5.52E+3nMAssay Description:Displacement of [3H]mesulergine from A9 cells stably expressing rat 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50026778(2-(2,5-Dimethoxy-phenyl)-ethylamine | 2-(2,5-dimet...)
Affinity DataKi:  6.40E+3nMAssay Description:Binding affinity against rat 5-hydroxytryptamine 2C receptor using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed