BDBM50026263 CHEMBL3358469::US20230348415, Compound (+-)-44

SMILES OC(=O)C1CCCN1C(=O)N1CCC(CC1)c1ccccc1C(F)(F)F

InChI Key InChIKey=ZIHYPADJFCDURR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50026263   

TargetRetinol-binding protein 4(Human)
Albany Molecular Research

Curated by ChEMBL
LigandPNGBDBM50026263(CHEMBL3358469 | US20230348415, Compound (+-)-44)
Affinity DataIC50: 3.00E+3nMAssay Description:Displacement of [3H]retinol from biotinylated human RBP4 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details Article
PubMed
TargetRetinol-binding protein(Human)
Columbia University

US Patent
LigandPNGBDBM50026263(CHEMBL3358469 | US20230348415, Compound (+-)-44)
Affinity DataIC50: 80nMAssay Description:Compound binding to RBP4 was assessed in the radiometric scintillation proximity (SPA) assay that was previously described (Cioffi, C. L. et al. 2014...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
Go to US Patent

TargetRetinol-binding protein(Human)
Columbia University

US Patent
LigandPNGBDBM50026263(CHEMBL3358469 | US20230348415, Compound (+-)-44)
Affinity DataIC50: 2.85E+3nMAssay Description:Compound binding to TTR was assessed in the fluorescence polarization assay. The assay measured competitive displacement of the fluorescent probe, FI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
Go to US Patent