BDBM50025945 CHEMBL3144416::{1-[1-{3-[1-(1-Carbamoyl-2-phenyl-ethylcarbamoyl)-3-methyl-butylcarbamoyl]-1-cyclohexylmethyl-2-hydroxy-propylcarbamoyl}-2-(1H-imidazol-4-yl)-ethylcarbamoyl]-2-phenyl-ethyl}-carbamic acid tert-butyl ester

SMILES CC(C)C[C@H](NC(=O)C[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

InChI Key InChIKey=WHSFNOLLOMZGRJ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50025945   

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50025945({1-[1-{3-[1-(1-Carbamoyl-2-phenyl-ethylcarbamoyl)-...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human kidney reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50025945({1-[1-{3-[1-(1-Carbamoyl-2-phenyl-ethylcarbamoyl)-...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50025945({1-[1-{3-[1-(1-Carbamoyl-2-phenyl-ethylcarbamoyl)-...)
Affinity DataKi:  0.880nMAssay Description:Inhibition of human kidney reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed