BDBM50025915 CHEMBL16622::[2-Benzyl-3-(formyl-hydroxy-amino)-propionylamino]-acetic acid

SMILES ON(CC(Cc1ccccc1)C(=O)NCC(O)=O)C=O

InChI Key InChIKey=XWNIIJNUTOPWBP-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50025915   

TargetAminopeptidase N(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50025915([2-Benzyl-3-(formyl-hydroxy-amino)-propionylamino]...)
Affinity DataIC50: 8.5nMAssay Description:Inhibitory activity against rabbit kidney aminopeptidase using 10 nM of [3H]Leu-enkephalin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50025915([2-Benzyl-3-(formyl-hydroxy-amino)-propionylamino]...)
Affinity DataIC50: 10nMAssay Description:50% inhibitory activity against enkephalinase purified from rat kidney with [3H]D-Ala2-Leu-enkephalin (20 nM) as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetThermolysin(Bacillus thermoproteolyticus)
Pohang University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50025915([2-Benzyl-3-(formyl-hydroxy-amino)-propionylamino]...)
Affinity DataKi:  3.40E+4nMpH: 7.2Assay Description:Inhibitory activity against thermolysin using 2-furylacryloyl-Gly-Leu-NH2 as substrate at pH 7.2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed