BDBM50025840 4-Amino-N-hydroxy-benzamide::4-aminobenzohydroxamic acid::CHEMBL155579

SMILES Nc1ccc(cc1)C(=O)NO

InChI Key InChIKey=DKGYBSPSUUVQRL-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50025840   

LigandPNGBDBM50025840(4-aminobenzohydroxamic acid | 4-Amino-N-hydroxy-be...)
Affinity DataIC50: 4.00E+5nMAssay Description:Compound was tested for its in vitro inhibitory activity against RBL-1 5-LO (time dependent)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50025840(4-aminobenzohydroxamic acid | 4-Amino-N-hydroxy-be...)
Affinity DataIC50: 3.98E+5nMAssay Description:Logarithmic value of inhibitory concentration against 5-lipoxygenase in rat basophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50025840(4-aminobenzohydroxamic acid | 4-Amino-N-hydroxy-be...)
Affinity DataIC50: 1.84E+4nMAssay Description:Inhibition of C-terminal His-tagged human HDAC3 (1 to 428 residues)/N-terminal GST tagged human NCOR2 (395 to 489) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50025840(4-aminobenzohydroxamic acid | 4-Amino-N-hydroxy-be...)
Affinity DataIC50: 1.84E+4nMAssay Description:Inhibition of C-terminal His-tagged human HDAC3 (1 to 428 residues)/N-terminal GST tagged human NCOR2 (395 to 489) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Preclinical R&D

Curated by ChEMBL
LigandPNGBDBM50025840(4-aminobenzohydroxamic acid | 4-Amino-N-hydroxy-be...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 insect cells pretreated with compound f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Preclinical R&D

Curated by ChEMBL
LigandPNGBDBM50025840(4-aminobenzohydroxamic acid | 4-Amino-N-hydroxy-be...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 insect cells pretreated with compound f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Italfarmaco

Curated by ChEMBL
LigandPNGBDBM50025840(4-aminobenzohydroxamic acid | 4-Amino-N-hydroxy-be...)
Affinity DataIC50: 7.14E+3nMAssay Description:Inhibition of recombinant human C-terminal His-tagged HDAC1 expressed in Sf9 insect cells using Fluor de Lys deacetylase or Fluor de Lys Green deacet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Preclinical R&D

Curated by ChEMBL
LigandPNGBDBM50025840(4-aminobenzohydroxamic acid | 4-Amino-N-hydroxy-be...)
Affinity DataIC50: 389nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged HDAC6 expressed in Sf9 insect cells using Fluor de Lys deacetylase or Fluor de Lys ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed