BDBM50025788 1-(4-Chloro-benzyl)-1,3-dihydro-imidazole-2-thione::CHEMBL306643

SMILES Clc1ccc(Cn2cc[nH]c2=S)cc1

InChI Key InChIKey=VCGVPCBVKFXEQA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50025788   

TargetDopamine beta-hydroxylase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50025788(1-(4-Chloro-benzyl)-1,3-dihydro-imidazole-2-thione...)
Affinity DataIC50: 9.60E+4nMAssay Description:Inhibitory Concentration against bovine Dopamine beta hydroxylase (DBH); Range is between (64-133)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Rat)
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50025788(1-(4-Chloro-benzyl)-1,3-dihydro-imidazole-2-thione...)
Affinity DataIC50: 9.55E+4nMAssay Description:Inhibition of dopamine beta-hydroxylase (DbetaH) in hypertensive rats when administered orally (or) intraperitoneallyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Human)
Harvard University

Curated by ChEMBL
LigandPNGBDBM50025788(1-(4-Chloro-benzyl)-1,3-dihydro-imidazole-2-thione...)
Affinity DataIC50: 9.55E+4nMAssay Description:Inhibition of dopamine beta-hydroxylase (DbetaH) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetDopamine beta-hydroxylase(Human)
Harvard University

Curated by ChEMBL
LigandPNGBDBM50025788(1-(4-Chloro-benzyl)-1,3-dihydro-imidazole-2-thione...)
Affinity DataIC50: 9.55E+4nMAssay Description:Inhibition of dopamine beta hydroxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed