BDBM50025582 7-Allyl-1,3-dimethyl-3,7-dihydro-purine-2,6-dione::CHEMBL24289

SMILES Cn1c2ncn(CC=C)c2c(=O)n(C)c1=O

InChI Key InChIKey=ZGIBYCLLIMGXEZ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50025582   

TargetAdenosine receptor A2b(Human)
National Institute of Diabetes & Digestive & Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50025582(7-Allyl-1,3-dimethyl-3,7-dihydro-purine-2,6-dione ...)
Affinity DataKi:  9.49E+3nMAssay Description:Binding affinity at human Adenosine A2B receptor expressed in HEK293 cells, using [125I]ABOPX as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50025582(7-Allyl-1,3-dimethyl-3,7-dihydro-purine-2,6-dione ...)
Affinity DataKi:  1.00E+4nMAssay Description:Compound was evaluated for its ability to antagonise cyclic [3H]AMP accumulation in [3H]adenine-labeled guinea pig cerebral cortical slices.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50025582(7-Allyl-1,3-dimethyl-3,7-dihydro-purine-2,6-dione ...)
Affinity DataKi:  3.30E+4nMAssay Description:Ability to inhibit binding of 1 nM [3H]cyclohexyladenosine to adenosine A1 receptor in rat cerebral cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed